Litcius/Paper detail

Discovery of two biotin-PEG4‑diarylidenyl piperidone prodrugs as potent antitumor agents with good efficacy, limited toxicity, and low resistance

Shuang-Qiang Liu, Zhi-Chen Mao, Yanli Xü, Xiao-Man Chen, Huiling Wang, Qi Wang, Jian-Hua Wei, Ri-Zhen Huang, Ye Zhang

2022Bioorganic Chemistry10 citationsDOI

Topics & Concepts

ChemistryProdrugPharmacologyToxicityDoxorubicinWestern blotLinkerBiochemistryChemotherapyOrganic chemistryBiologyGeneticsGeneComputer scienceOperating systemCancer therapeutics and mechanismsClick Chemistry and ApplicationsHIV/AIDS drug development and treatment
Discovery of two biotin-PEG4‑diarylidenyl piperidone prodrugs as potent antitumor agents with good efficacy, limited toxicity, and low resistance | Litcius