Effect of Axillary Dissection vs No Axillary Dissection on 10-Year Overall Survival Among Women With Invasive Breast Cancer and Sentinel Node Metastasis: The ACOSOG Z0011 (Alliance) Randomized Clinical Trial
Nora Hansen, Pat W. Whitworth, Pond R. Kelemen, Armando E. Giuliano, A. Marilyn Leitch, Linda McCall, Sukamal Saha, Karla V. Ballman, Peter Blumencranz, Meghan Brennan, David W. Ollila, Kelly K. Hunt, Monica Morrow, Peter D. Beitsch
Abstract
The results of the American College of Surgeons Oncology Group Z0011 (ACOSOG Z0011) trial were first reported in 2005 with a median follow-up of 6.3 years. Longer follow-up was necessary because the majority of the patients had estrogen receptor–positive tumors that may recur later in the disease course (the ACOSOG is now part of the Alliance for Clinical Trials in Oncology).
Topics & Concepts
MedicineAxillary DissectionBreast cancerSentinel nodeDissection (medical)Randomized controlled trialSurgeryGeneral surgeryCancerInternal medicineSentinel lymph nodeBreast Cancer Treatment StudiesCancer Treatment and PharmacologyBrain Metastases and Treatment