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Generic Molding Platform for Simple, Low‐Cost Fabrication of Polymeric Microneedles

Kedar Badnikar, Shreyas N. Jayadevi, Suman Pahal, Sukruth Sripada, Manjunatha M. Nayak, Praveen Kumar Vemula, Dinesh N. Subrahmanyam

2020Macromolecular Materials and Engineering10 citationsDOIOpen Access PDF

Abstract

Front Cover: In article number 2000072, Kedar Badnikar, Suman Pahal, and co-workers demonstrate a novel reconfigurable molding platform where polymeric microneedles with different geometric parameters can be fabricated with minimal setup requirements. The working of this novel molding platfom with variable aspect ratio capabilities is demonstrated in the cover image. Controlled rotary movement of the central adjustment bolt with respect to 50 μm per division graduations on circular a scale helps in precise adjustment. Successive rotary movements of 45° results in microneedle height resolution of 100 μm. Any other resolution is possible depending on the pitch of the adjustment bolt and angular pitch on the circular scale. This concept can be scaled up for microneedle production from the μm to the mm range in a simple and controllable way, impacting the translation of microneedle-based applications from laboratory to market.

Topics & Concepts

Materials scienceMolding (decorative)FabricationScale (ratio)Mechanical engineeringCover (algebra)Composite materialNanotechnologyPhysicsQuantum mechanicsAlternative medicineEngineeringPathologyMedicineAdvancements in Transdermal Drug DeliveryAdvanced Fiber Optic Sensors