Neonatal Anesthesia by Ketamine in Neonatal Rats Inhibits the Proliferation and Differentiation of Hippocampal Neural Stem Cells and Decreases Neurocognitive Function in Adulthood via Inhibition of the Notch1 Signaling Pathway
He Huang, Chao Zhao, Hu Qian, Qiang Liu, Yi-Man Sun, Chen Chen, Hui Huang, Chenghua Zhou, Yuqing Wu
Topics & Concepts
NeurogenesisHippocampal formationMorris water navigation taskDentate gyrusHippocampusNeural stem cellNotch signaling pathwayHES1KetaminePharmacologyNeuroscienceEndocrinologyBiologyInternal medicineMedicineSignal transductionCell biologyStem cellAnesthesia and Neurotoxicity ResearchIntensive Care Unit Cognitive DisordersNeurogenesis and neuroplasticity mechanisms