Protein complexes and neighborhoods driving autophagy
Devanarayanan Siva Sankar, Jörn Dengjel
Abstract
: AMPK: AMP-activated protein kinase; AP-MS: affinity purification-mass spectrometry; APEX2: ascorbate peroxidase-2; ATG: autophagy related; BioID: proximity-dependent biotin identification; ER: endoplasmic reticulum; GFP: green fluorescent protein; iTRAQ: isobaric tag for relative and absolute quantification; MS: mass spectrometry; PCA: protein-fragment complementation assay; PL-MS: proximity labeling-mass spectrometry; PtdIns3P: phosphatidylinositol-3-phosphate; PTM: posttranslational modification; PUP-IT: pupylation-based interaction tagging; RFP: red fluorescent protein; SILAC: stable isotope labeling by amino acids in cell culture; TAP: tandem affinity purification; TMT: tandem mass tag.
Topics & Concepts
AutophagyBiologyCell biologyBiogenesisAutophagosomeProteomicsProtein aggregationProtein degradationBAG3CytoplasmATG8Transport proteinOrganelleEndosomeComputational biologyIntracellularBiochemistryGeneApoptosisBiotin and Related StudiesCellular transport and secretionCalcium signaling and nucleotide metabolism