Switchable β-alkylation of Secondary Alcohols with Primary Alcohols by a Well-Defined Cobalt Catalyst
Bedraj Pandey, Shi Xu, Keying Ding
Abstract
β-alkylation of secondary alcohols with primary alcohols to selectively generate alcohols by a well-defined Co catalyst is presented. Remarkably, a low catalyst loading of 0.7 mol % can be employed for the reaction. More significantly, this study represents the first Co-catalyzed switchable alcohol/ketone synthesis by simply manipulating the reaction parameters. In addition, the transformation is environmentally friendly, with water as the only byproduct.
Topics & Concepts
ChemistryCatalysisAlkylationPrimary (astronomy)AlcoholCobaltKetoneOrganic chemistryEnvironmentally friendlyPrimary alcoholAlcohol oxidationAstronomyBiologyEcologyPhysicsAsymmetric Hydrogenation and CatalysisCatalysis for Biomass ConversionCarbon dioxide utilization in catalysis