Targeted delivery of cancer drug paclitaxel to chordomas tumor cells via an RNA nanoparticle harboring an EGFR aptamer
Dan Xiao, Yongxiong Huang, Shuaihao Huang, Jianxiong Zhuang, P Chen, Yi Wang, Lei Zhang
Topics & Concepts
AptamerPaclitaxelDrug deliveryEpidermal growth factor receptorChemistryFlow cytometryCancer researchCancer cellTargeted drug deliveryCell cultureCellSmall interfering RNADrugRNACancerMolecular biologyPharmacologyReceptorBiologyMedicineBiochemistryInternal medicineGeneticsOrganic chemistryGeneRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesinterferon and immune responses