MD-DATA: the legacy of the ABC Consortium
Modesto Orozco
Abstract
The ABC Consortium has been generating nucleic-acids MD trajectories for more than 20 years. This brief comment highlights the importance of this data for the field, which triggered a number of critical studies, including force-field parameterization and development of new coarse-grained and mesoscopic models. With the world entering into a new data-driven era led by artificial intelligence, where data is becoming more essential than ever, the ABC initiative is leading the way for nucleic acid flexibility.
Topics & Concepts
Flexibility (engineering)Field (mathematics)Mesoscopic physicsComputer scienceNucleic acidData scienceComputational biologyBiologyPhysicsMathematicsGeneticsPure mathematicsQuantum mechanicsStatisticsDNA and Nucleic Acid ChemistryBacteriophages and microbial interactionsAdvanced biosensing and bioanalysis techniques