Litcius/Paper detail

Between promise and peril: role of suzetrigine as a non-opioid analgesic

Jay Karri, Ryan S. D’Souza, Steven P. Cohen

2025BMJ Medicine13 citationsDOIOpen Access PDF

Abstract

Despite recent approval from the US Food and Drug Administration, the clinical benefits of suzetrigine remain modest and contestedIn the current landscape of the opioid crisis, which was responsible for over 100,000 overdose deaths in the United States in 2022 alone, interest in the development of non-opioid analgesics has been considerable.

Topics & Concepts

AnalgesicOpioidMedicinePharmacologyInternal medicineReceptorPain Management and Placebo EffectAnesthesia and Pain ManagementPain Mechanisms and Treatments