Methemoglobinemia in Patient with G6PD Deficiency and SARS-CoV-2 Infection
Kieran Palmer, Jonathan Dick, Winifred French, Lajos Flóró, Martin L. Ford
Abstract
We report a case of intravascular hemolysis and methemoglobinemia, precipitated by severe acute respiratory syndrome coronavirus 2 infection, in a patient with undiagnosed glucose-6-phosphate dehydrogenase deficiency. Clinicians should be aware of this complication of coronavirus disease as a cause of error in pulse oximetry and a potential risk for drug-induced hemolysis.
Topics & Concepts
MethemoglobinemiaHemolysisMedicinePulse oximetryPandemicComplicationHemolytic anemiaRhabdomyolysisGlucose-6-phosphate dehydrogenase deficiencyInfectious disease (medical specialty)Intensive care medicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)DiseaseImmunologyVirologyInternal medicineAnesthesiaNeonatal Health and BiochemistryMethemoglobinemia and Tumor Lysis SyndromeErythrocyte Function and Pathophysiology