Litcius/Paper detail

Synthesis, biological evaluation and mechanism study of a novel indole-pyridine chalcone derivative as antiproliferative agent against tumor cells through dual targeting tubulin and HK2

Mengzhu Zheng, Guangyuan Liu, Yawei Han, Pengyu Qian, Mingze Wu, Ming Xiang, Yirong Zhou

2024European Journal of Medicinal Chemistry15 citationsDOIOpen Access PDF

Topics & Concepts

ChalconeChemistryIndole testTubulinDerivative (finance)PyridineStereochemistryDual (grammatical number)Mechanism (biology)Biological activityBiochemistryCombinatorial chemistryIn vitroCell biologyMedicinal chemistryMicrotubuleArtEpistemologyFinancial economicsPhilosophyEconomicsLiteratureBiologySynthesis and biological activitySynthesis and Biological EvaluationSynthesis and Characterization of Heterocyclic Compounds