Toward Realistic Dosimetry <i>In Vitro</i>: Determining Effective Concentrations of Test Substances in Cell Culture and Their Prediction by an <i>In Silico</i> Mass Balance Model
Dunja Dimitrijevic, Eric Fabian, Beate Nicol, Dorothee Funk-Weyer, Robert Landsiedel
Abstract
, which were also relatively well predicted by the mass balance model.
Topics & Concepts
LipophilicityChemistryIn silicoIn vitroCytosolChromatographyCell cultureBiochemistryBiologyGeneGeneticsEnzymeEffects and risks of endocrine disrupting chemicalsCarcinogens and Genotoxicity AssessmentToxic Organic Pollutants Impact