Intertwined chemistry of hydroxyl hydrogen-bond donors, epoxides and isocyanates in the organocatalytic synthesis of oxazolidinones <i>versus</i> isocyanurates: rational catalytic investigation and mechanistic understanding
Prapussorn Yingcharoen, Wuttichai Natongchai, Albert Poater, Valerio D’Elia
Abstract
The efficiency and chemoselectivity of the cycloaddition of isocyanates to epoxides to afford oxazolidinones were investigated using hydroxyl hydrogen-bond donors as organocatalysts.
Topics & Concepts
ChemoselectivityCatalysisChemistryCycloadditionOrganocatalysisHydrogen bondOrganic chemistryHydrogenCombinatorial chemistryEnantioselective synthesisMoleculeCarbon dioxide utilization in catalysisChemical Synthesis and ReactionsSulfur-Based Synthesis Techniques