Transition metal(<scp>ii</scp>) complexes of halogenated derivatives of (<i>E</i>)-4-(2-(pyridin-2-ylmethylene)hydrazinyl)quinazoline: structure, antioxidant activity, DNA-binding DNA photocleavage, interaction with albumin and<i>in silico</i>studies
Chrisoula Kakoulidou, Christos T. Chasapis, Antonios G. Hatzidimitriou, Konstantina C. Fylaktakidou, George Psomas
Abstract
Six transition metal( ii ) complexes with halogenated quinazoline derivatives as ligands were characterized and evaluated for interaction with calf-thymus DNA, photocleavage of plasmid-DNA, affinity for bovine serum albumin, and antioxidant activity.
Topics & Concepts
ChemistryBovine serum albuminMethyleneDNAQuinazolineMetal ions in aqueous solutionMetalMedicinal chemistryNuclear chemistryStereochemistryBiochemistryOrganic chemistryMetal complexes synthesis and propertiesSynthesis and Characterization of Heterocyclic CompoundsQuinazolinone synthesis and applications