Rutin alleviates EndMT by restoring autophagy through inhibiting HDAC1 via PI3K/AKT/mTOR pathway in diabetic kidney disease
Ruixue Dong, Xi Zhang, Yadi Liu, Tingting Zhao, Zhongyan Sun, Peiyu Liu, Qian Xiang, Jianfeng Xiong, Xi‐Wen Du, Xifei Yang, Dingkun Gui, Youhua Xu
Topics & Concepts
AutophagyPI3K/AKT/mTOR pathwayRutinProtein kinase BHDAC1ChemistryMedicineCancer researchSignal transductionPharmacologyCell biologyBiologyApoptosisBiochemistryAntioxidantHistone deacetylaseHistoneGeneAutophagy in Disease and TherapyHistone Deacetylase Inhibitors ResearchAntioxidants, Aging, Portulaca oleracea