Effect of hesperidin conjugated with golden nanoparticles on phagocytic activity: In vitro study
Hanaa M. Waheeb, Ghassan M. Sulaiman, Majid S. Jabir
Abstract
Hesperidin is one of the flavonoids and it recognized to possess various biomedical potentials. Golden nanoparticles have been used in various applications covering both in vivo and in vitro biomedical diagnosis. To evaluate the stimulation activity of phagocytic Index (PI), the golden nanoparticle–conjugated hesperidin (AuNPs-Hd) were used in present study. The effect of AuNPs-Hd showed a considerable increase (85%) in contrast with PI of Gold nanoparticles which was (66%) and Hesperidin which was (51%). while, PI of blood sample that indicate the control was (20%). These data provide the evidence about the impact of AuNPs-Hsp on phagocytic cells and the nanoparticles were ingested by these cells.