PPAB001, a novel bispecific antibody against CD47 and CD24, enhances anti-PD-L1 efficacy in triple-negative breast cancer via reprogramming tumor-associated macrophages towards M1 phenotype
Yun Yang, Yun Yang, Jianqin Li, Jing Zhang, He Wu, Yanlian Yang, Yanlian Yang, Huaizu Guo, Dapeng Zhang, Chunpo Ge, Bei Zhou, Ling Ma, Weihua Dong
Topics & Concepts
ReprogrammingCD47AntibodyTriple-negative breast cancerBreast cancerCancer researchPhenotypeCancerMedicineImmunologyBiologyInternal medicineGeneticsCellGenePhagocytosis and Immune RegulationImmune cells in cancerImmunotherapy and Immune Responses