Copper catalyzed cyano-sulfonylation of allenes <i>via</i> the insertion of sulfur dioxide toward the synthesis of (<i>E</i>)-α-cyanomethyl vinylsulfones
Yue Li, Xuemei Zhang, Zhong Lian
Abstract
An efficient and practical method for highly regio- and stereo-selective cyanosulfonylation of allenes by inserting sulfur dioxide to synthesize useful ( E )-α-cyanomethyl vinylsulfones has been explored.
Topics & Concepts
ChemistryCatalysisSulfurSulfur dioxideCopperMedicinal chemistryOrganic chemistrySulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCyberloafing and Workplace Behavior