Electrochemical-Promoted Synthesis of 2-Thiazolines via Selenylation/Cyclization of <i>N</i>-Allylthioamides
Chao Pan, Peng Liu, Anguo Wu, Ming Li, Li‐Rong Wen, Weisi Guo
Abstract
建立了一种电化学促进N-烯丙基硫代酰胺的串联硒化/环化新方法，用来制备含硒官能团的2-噻唑啉衍生物.该方法反应条件温和，底物范围广.初步的机理研究表明，反应过程中有硒自由基的参与.该方法操作简单且无需使用催化剂、过渡金属和氧化剂.
Topics & Concepts
ChemistryElectrochemistryMedicinal chemistryCombinatorial chemistryPhysical chemistryElectrodeSynthesis and Characterization of Heterocyclic CompoundsSynthesis and Reactivity of Sulfur-Containing CompoundsQuinazolinone synthesis and applications