Hybrid Nanoplatforms Based on Photosensitizers and Metal/Covalent Organic Frameworks for Improved Cancer Synergistic Treatment Nano-Delivery Systems
Aviwe Magadla
Abstract
Researchers have extensively investigated photosensitizer (PS) derivatives for various applications due to their superior photophysical and electrochemical properties. However, inherent problems, such as instability and self-quenching under physiological conditions, limit their biological applications. Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) represent two relatively new material types. These materials have high surface areas and permanent porosity, and they show a tremendous deal of potential for applications like these. This review summarizes key synthesis processes and highlights recent advancements in integrating PS-based COF and MOF nanocarriers for biomedical applications while addressing potential obstacles and prospects.