A sleep-like state in <i>Hydra</i> unravels conserved sleep mechanisms during the evolutionary development of the central nervous system
Hiroyuki J. Kanaya, Sungeon Park, Ji-hyung Kim, Junko Kusumi, Sofian Krenenou, Etsuko Sawatari, Aya Sato, Jongbin Lee, Hyunwoo Bang, Yoshitaka Kobayakawa, Chunghun Lim, Taichi Q. Itoh
Abstract
, suggesting the evolutionary switch of their sleep-regulatory functions. Thus, sleep-relevant physiology and sleep-regulatory components may have already been acquired at molecular levels in a brain-less metazoan phylum and reprogrammed accordingly.
Topics & Concepts
Lernaean HydraBiologySleep (system call)NeuroscienceUltradian rhythmCircadian rhythmCell biologyComputer scienceOperating systemMarine Invertebrate Physiology and EcologySleep and Wakefulness ResearchSphingolipid Metabolism and Signaling