Mechanisms underlying Nrf2 nuclear translocation by non-lethal levels of hydrogen peroxide: p38 MAPK-dependent neutral sphingomyelinase2 membrane trafficking and ceramide/PKCζ/CK2 signaling
Tetsuro Ishii, Eiji Warabi, Giovanni E. Mann
Topics & Concepts
Cell biologyCeramideKEAP1ChemistryGlutathioneSphingomyelinKinasep38 mitogen-activated protein kinasesSignal transductionPhosphorylationMAPK/ERK pathwayOxidative stressBiologyBiochemistryTranscription factorMembraneEnzymeGeneApoptosisGenomics, phytochemicals, and oxidative stressPlant Stress Responses and ToleranceSphingolipid Metabolism and Signaling