Cyanidin-3-O-glucoside and its metabolite protocatechuic acid ameliorate 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced cytotoxicity in HepG2 cells by regulating apoptotic and Nrf2/p62 pathways
Lei Zhao, Na Zhou, Huimin Zhang, Fei Pan, Xin Ai, Yong Wang, Shuai Hao, Chengtao Wang
Topics & Concepts
CytotoxicityChemistryApoptosisMetaboliteXIAPBiochemistryProtocatechuic acidCaspaseProgrammed cell deathAntioxidantIn vitroVitamin C and Antioxidants ResearchGenomics, phytochemicals, and oxidative stressDrug-Induced Hepatotoxicity and Protection