Identification of morpholine based hydroxylamine analogues: selective inhibitors of MARK4/Par-1d causing cancer cell death through apoptosis
Mudasir Nabi Peerzada, Parvez Κhan, Nashrah Sharif Khan, Aysha Gaur, Fernando Avecilla, Md. Imtaiyaz Hassan, Amir Azam
Abstract
Interaction of compound<bold>32</bold>with various active site residues of MARK4.
Topics & Concepts
ChemistryHydroxylamineMorpholineApoptosisProgrammed cell deathIdentification (biology)StereochemistryBiochemistryOrganic chemistryBotanyBiologyPhytochemicals and Antioxidant ActivitiesMicrobial Metabolism and ApplicationsMelanoma and MAPK Pathways