The m6A readers <i>YTHDF1</i> and <i>YTHDF3</i> aberrations associated with metastasis and predict poor prognosis in breast cancer patients.
Anita Ramesh, Paramasivam Arumugam, Jayaseelan Vijayashree Priyadharsini, Chitra Srinivasan
Abstract
were associated with poor prognosis of breast cancer patients. Therefore, YTHDF1 and YTHDF3 serve a crucial role in the pathogenesis of breast cancer, which are potentially useful for prognosis stratification and therapeutic target for breast cancer.
Topics & Concepts
CarcinogenesisBreast cancerMetastasisCancer researchCancerDownregulation and upregulationBiologyOncologyInternal medicineMedicineGeneGeneticsRNA modifications and cancerCancer-related gene regulationCancer-related molecular mechanisms research