Visible light-mediated metal-free alkyl Suzuki–Miyaura coupling of alkyl halides and alkenylboronic acids/esters: a green method for the synthesis of allyl difluoride derivatives
Chuan‐Hua Qu, Xiao Yan, Shu‐Ting Li, Jianbo Liu, Zhigang Xu, Zhong‐Zhu Chen, Dianyong Tang, Huanxiang Liu, Gui‐Ting Song
Abstract
Halogen bonding-assisted C sp 3 –Br homolysis and bromine radical-mediated oxidative deboronation make visible-light-driven photocatalyst-free alkyl Suzuki–Miyaura coupling of alkenylboronic acids/esters with α-bromodifluoroacylarenes accessible.
Topics & Concepts
AlkylHalideChemistryMetalOrganic chemistryCoupling (piping)DifluorideMaterials scienceMetallurgyRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques