Decreased expression of IDH1 by chronic unpredictable stress suppresses proliferation and accelerates senescence of granulosa cells through ROS activated MAPK signaling pathways
Junyan Sun, Ying Guo, Yihui Fan, Qian Wang, Qiuwan Zhang, Dongmei Lai
Topics & Concepts
Cell biologyMAPK/ERK pathwayGene knockdownSenescenceCell growthSignal transductionBiologyp38 mitogen-activated protein kinasesOxidative stressChemistryApoptosisBiochemistryReproductive Biology and FertilityCircadian rhythm and melatoninGenetics, Aging, and Longevity in Model Organisms