LncRNA MRAK159688 facilitates morphine tolerance by promoting REST-mediated inhibition of mu opioid receptor in rats
Meiling Deng, Zengli Zhang, Manyu Xing, Xia Liang, Zhengyiqi Li, Jing Wu, Shasha Jiang, Yingqi Weng, Qulian Guo, Wangyuan Zou
Topics & Concepts
MorphineDownregulation and upregulationPharmacologyHyperalgesiaDrug toleranceμ-opioid receptorOpioidGene silencingChemistryMedicineReceptorNociceptionInternal medicineBiochemistryGeneCancer-related molecular mechanisms researchImmune Cell Function and Interaction