Light-responsive biomaterials for ocular drug delivery
Hend A. M. Abdelmohsen, Nikki A. Copeland, John G. Hardy
Abstract
Light-responsive biomaterials can be used for the delivery of therapeutic drugs and nucleic acids, where the tunable/precise delivery of payload highlights the potential of such biomaterials for treating a variety of conditions. The translucency of eyes and advances of laser technology in ophthalmology make light-responsive delivery of drugs feasible. Importantly, light can be applied in a non-invasive fashion; therefore, light-triggered drug delivery systems have great potential for clinical impact. This review will examine various types of light-responsive polymers and the chemistry that underpins their application as ophthalmic drug delivery systems.
Topics & Concepts
Drug deliveryNanotechnologyPayload (computing)Computer scienceMaterials scienceComputer networkNetwork packetPhotochromic and Fluorescence ChemistryPhotoreceptor and optogenetics researchNanoplatforms for cancer theranostics