STAT3 inhibition protects against neuroinflammation and BACE1 upregulation induced by systemic inflammation
Périne Millot, Carine San, Evangéline Bennana, Baptiste Porte, N. Vignal, Jacques Hugon, Claire Paquet, Benoît Hosten, François Mouton‐Liger
Topics & Concepts
NeuroinflammationSTAT3Systemic inflammationSTAT proteinSystemic administrationInflammationDownregulation and upregulationMicrogliaTumor necrosis factor alphaCytokineSickness behaviorPharmacologyChemistryPhosphorylationMedicineImmunologyBiologyCell biologyIn vivoBiochemistryBiotechnologyGeneAlzheimer's disease research and treatmentsTryptophan and brain disordersImmune responses and vaccinations