EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer
Ke Gong, Gao Guo, Nishah Panchani, Matthew E. Bender, David E. Gerber, John D. Minna, Farjana Fattah, Boning Gao, Michael Peyton, Kemp H. Kernstine, Bipasha Mukherjee, Sandeep Burma, Cheng-Ming Chiang, Shanrong Zhang, Adwait Amod Sathe, Chao Xing, Kathryn H. Dao, Dawen Zhao, Esra A. Akbay, Amyn A. Habib
Topics & Concepts
Cancer researchUbiquitin ligaseErlotinibLung cancerKRASDownregulation and upregulationEGFR inhibitorsSignal transductionEpidermal growth factor receptorMedicineUbiquitinCancerChemistryBiologyInternal medicineCell biologyBiochemistryGeneColorectal cancerinterferon and immune responsesLung Cancer Treatments and MutationsCytokine Signaling Pathways and Interactions