A novel target TAX1BP1 and P38/Nrf2 pathway independently involved in the anti-neuroinflammatory effect of isobavachalcone
Zhipeng Li, Qiaoyun Wang, Haiyun Luan, Ming Yang, Yanni Li, Geng Tian, Wenbin He
Topics & Concepts
MicrogliaDownregulation and upregulationIn vivoNeuroinflammationChemistryInhibitory postsynaptic potentialp38 mitogen-activated protein kinasesIn vitroNeuroscienceSignal transductionCell biologyBiologyInflammationMAPK/ERK pathwayBiochemistryImmunologyBiotechnologyGeneNeuroinflammation and Neurodegeneration MechanismsBioactive natural compoundsGenomics, phytochemicals, and oxidative stress