Co-deletion of Lrp5 and Lrp6 in the skeleton severely diminishes bone gain from sclerostin antibody administration
Kyung‐Eun Lim, Whitney A. Bullock, Daniel J. Horan, Bart O. Williams, Matthew L. Warman, Alexander G. Robling
Topics & Concepts
SclerostinLRP5Wnt signaling pathwayLRP6OsteoblastOsteocyteEndocrinologyInternal medicineChemistryBiologyMedicineCell biologySignal transductionBiochemistryIn vitroBone health and treatmentsWnt/β-catenin signaling in development and cancerBone health and osteoporosis research