Recent advances in radiotherapy of breast cancer
Jan Haussmann, Stefanie Corradini, Carolin Nestle-Kraemling, Edwin Bölke, Freddy Joel Djiepmo Njanang, Bálint Tamaskovics, Klaus Orth, Eugen Ruckhaeberle, Tanja Fehm, Svjetlana Mohrmann, Ioannis Simiantonakis, Wilfried Budach, Christiane Matuschek
Abstract
Radiation therapy is an integral part of the multidisciplinary management of breast cancer. Regional lymph node irradiation in younger trials seems to provide superior target coverage as well as a reduction in long-term toxicity resulting in a small benefit in the overall survival rate. For partial breast irradiation there are now two large trials available which support the role of partial breast irradiation in low risk breast cancer patients. Multiple randomized trials have established that a sequentially applied dose to the tumor bed improves local control with the cost of worse cosmetic results.