Solvent electrospinning amorphous solid dispersions with high itraconazole, celecoxib, mebendazole and fenofibrate drug loading and release potential
Jana Becelaere, Olmo Frateur, Ella Schoolaert, Valérie Vanhoorne, Dagmar D’hooge, Chris Vervaet, Richard Hoogenboom, Karen De Clerck
Topics & Concepts
ElectrospinningChemical engineeringDifferential scanning calorimetryAmorphous solidCrystallinityMaterials scienceSolubilityPolyvinylpyrrolidoneCrystallizationMiscibilityDissolutionExcipientPolymerChemistryOrganic chemistryChromatographyPolymer chemistryComposite materialThermodynamicsEngineeringPhysicsElectrospun Nanofibers in Biomedical ApplicationsPolymer Surface Interaction Studiesbiodegradable polymer synthesis and properties