Omeprazole induces vascular remodeling by mechanisms involving xanthine oxidoreductase and matrix metalloproteinase activation
Renato C. Nogueira, Lucas C. Pinheiro, Jéssica M. Sanches-Lopes, Juliana Montenegro Parente, Gustavo H. Oliveira‐Paula, Sandra O. Conde, Michele M. Castro, José E. Tanus‐Santos
Topics & Concepts
OmeprazoleZymographyAllopurinolOxidative stressPharmacologyChemistryEndothelial dysfunctionMatrix metalloproteinaseInternal medicineReactive oxygen speciesXanthine dehydrogenaseEndocrinologyMedicineXanthine oxidaseBiochemistryEnzymeNitric Oxide and Endothelin EffectsGout, Hyperuricemia, Uric AcidPulmonary Hypertension Research and Treatments