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Transcription Inhibitors with XRE DNA-Binding and Cupin Signal-Sensing Domains Drive Metabolic Diversification in <i>Pseudomonas</i>

Julian Trouillon, Michel Ragno, Victor Simon, Ina Attrée, Sylvie Elsen

2021mSystems41 citationsDOIOpen Access PDF

Abstract

Bacteria of the Pseudomonas genus, including the major human pathogen Pseudomonas aeruginosa , are known for their complex regulatory networks and high number of transcription factors, which contribute to their impressive adaptive ability. However, even in the most studied species, most of the regulators are still uncharacterized.

Topics & Concepts

PseudomonasBiologyTranscription (linguistics)Pseudomonas aeruginosaTranscription factorBacteriaDNAGeneticsComputational biologyGeneMicrobiologyLinguisticsPhilosophyBacterial Genetics and BiotechnologyGenomics and Phylogenetic StudiesBacterial biofilms and quorum sensing