Discovering the role of N-heterocyclic carbene as hydrogen borrowing organocatalyst: metal-free, direct<i>N</i>-alkylation of amines with benzyl alcohols
Richa Sharma, Abdul Rahaman T A, Janmejaya Sen, I. V. Mashevskaya, Sandeep Chaudhary
Abstract
A highly sustainable, bench-stable, inexpensive, non-toxic and commercially available N-heterocyclic carbene based hydrogen borrowing organocatalyst for the direct N-alkylation of amines with alcohols is reported.
Topics & Concepts
ChemistryCarbeneAlkylationOrganic chemistryHydrogenMetalCatalysisCombinatorial chemistryAsymmetric Hydrogenation and CatalysisCarbon dioxide utilization in catalysisCatalytic Cross-Coupling Reactions