Effectively removing the homodimer in bispecific antibodies by weak partitioning mode of anion exchange chromatography
Xiaoying Liang, Qingquan He, Guohong Qin, Guozhu Li, Qian Li, Huanghong Tan, Zichen Wang, Mengni Fan, Dan Xu
Topics & Concepts
ChemistryPolishingIon chromatographyElutionChromatographyIon exchangeRecombinant DNAAffinity chromatographyYield (engineering)PairingBiophysicsIonBiochemistryEnzymeOrganic chemistryGeneMaterials scienceMetallurgyPhysicsBiologyQuantum mechanicsSuperconductivityComposite materialMonoclonal and Polyclonal Antibodies ResearchProtein purification and stabilityGlycosylation and Glycoproteins Research