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Hierarchical Porous Aggregate-Enabled Chromatography-Inspired Single-Sensor E-Nose for Volatile Monitoring

Haowen Guo, Taoping Liu, Xingchun Zhai, Zhuohua Qu, Yongheng Zhang, Junjie Wen, Shi-Fan Xue, Junjie Li, Jing Tang, Tan‐Phat Huynh, Guijun Li, Guoyue Shi, Min Zhang

2025ACS Sensors13 citationsDOIOpen Access PDF

Abstract

Monitoring volatile organic compounds (VOCs) is crucial for ensuring safety and health. In this study, we introduce a strategy to engineer a chromatography-inspired single-sensor (CISS) e-nose tailored for VOC monitoring. This approach overcomes the limitations of traditional methodologies and conventional e-noses. A hierarchical porous multicomponent aggregate, named CuP@G, was initially developed as the sole sensor material. This aggregate integrates a Cu 2+ –polydopamine (CuP) network with reduced graphene oxide, enhancing its chemoresistive properties. Using laser processing, we fabricated a grooved laser-induced graphene interdigitated electrode that is loaded with CuP@G ink and subsequently integrated into a compact laser-engraved microchamber. This process results in the production of the CISS e-nose. Notably, this e-nose enables swift, reversible, and precise detection of various VOCs using a time-space-resolved methodology. The developed module, known for its affordability and portability, is especially suitable for the point-of-care testing (POCT) of VOCs. Consequently, our research advances the development of streamlined cost-effective e-noses that are essential for proficient VOC monitoring.

Topics & Concepts

Aggregate (composite)PorosityChromatographyElectronic noseMaterials scienceChemistryNanotechnologyOrganic chemistryAdvanced Chemical Sensor TechnologiesGas Sensing Nanomaterials and SensorsAnalytical Chemistry and Sensors