Two siblings presenting with novel ADA2 variants, lymphoproliferation, persistence of large granular lymphocytes, and T-cell perturbations

Francesco Saettini, Grazia Fazio, Paola Corti, Manuel Quadri, Cristina Bugarin, Giuseppe Gaipa, Federica Penco, Daniele Moratto, Marcho Chiarini, Manuela Baronio, Luisa Gazzurelli, Luisa Imberti, Simone Paghera, Silvia Giliani, Giovanni Cazzaniga, Alessandro Plebani, Raffaele Badolato, Vassilios Lougaris, Marco Gattorno, Andrea Biondi