Clonal replacement of tumor-specific T cells following PD-1 blockade
Kathryn E. Yost, Ansuman T. Satpathy, Daniel K. Wells, Yanyan Qi, Chunlin Wang, Robin Kageyama, Katherine McNamara, Jeffrey M. Granja, Kavita Y. Sarin, Ryanne A. Brown, Rohit Gupta, Christina Curtis, Samantha Bucktrout, Mark M. Davis, Anne Lynn S. Chang, Howard Y. Chang
Topics & Concepts
Cytotoxic T cellCD8T cellBiologyCancer researchBlockadeCellTumor-infiltrating lymphocytesImmune checkpointImmunologyclone (Java method)ImmunotherapyReceptorImmune systemIn vitroGeneticsGeneCAR-T cell therapy researchCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction