Escherichia coli Sequence Type 457 Is an Emerging Extended-Spectrum-β-Lactam-Resistant Lineage with Reservoirs in Wildlife and Food-Producing Animals
Kristina Nešporová, Ethan R. Wyrsch, Adam Valček, Ibrahim Bitar, Khin Chaw, Patrick N. A. Harris, Jaroslav Hrabák, Ivan Literák, Steven P. Djordjevic, Monika Dolejská
Abstract
Silver gulls carry phylogenetically diverse Escherichia coli , including globally dominant extraintestinal pathogenic E. coli (ExPEC) sequence types and pandemic ExPEC-ST131 clades; however, our large-scale study (504 samples) on silver gulls nesting off the coast of New South Wales identified E. coli ST457 as the most prevalent. A phylogenetic analysis of whole-genome sequences (WGS) of 138 ST457 samples comprising 42 from gulls, 2 from humans (Australia), and 14 from poultry farmed in Paraguay were compared with 80 WGS deposited in public databases from diverse sources and countries.