Dual Probes for Positron Emission Tomography (PET) and Fluorescence Imaging (FI) of Cancer
Richard Yuen, F. G. West, Frank Wuest
Abstract
Dual probes that possess positron emission tomography (PET) and fluorescence imaging (FI) capabilities are precision medicine tools that can be used to improve patient care and outcomes. Detecting tumor lesions using PET, an extremely sensitive technique, coupled with fluorescence-guided surgical resection of said tumor lesions can maximize the removal of cancerous tissue. The development of novel molecular probes is important for targeting different biomarkers as every individual case of cancer has different characteristics. This short review will discuss some aspects of dual PET/FI probes and explore the recently reported examples.
Topics & Concepts
Positron emission tomographyMolecular imagingPet imagingFluorescence-lifetime imaging microscopyMedicineCancerFluorescenceMedical physicsNuclear medicineRadiologyOpticsPhysicsBiologyInternal medicineBiotechnologyIn vivoNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryRadiopharmaceutical Chemistry and Applications