Topical antimicrobial peptide omiganan recovers cutaneous dysbiosis but does not improve clinical symptoms in patients with mild to moderate atopic dermatitis in a phase 2 randomized controlled trial
Tessa Niemeyer‐van der Kolk, Thomas P. Buters, Lara Krouwels, Jiry Boltjes, Marieke L. de Kam, Hein van der Wall, Dirk C.J.G. van Alewijk, Ellen H. A. van den Munckhof, Martin Becker, Gary Feiss, Edwin F. Florencia, Errol P. Prens, Matthijs Moerland, Jacobus Burggraaf, Robert Rißmann, Martijn B. A. van Doorn
Topics & Concepts
MedicineTolerabilityAtopic dermatitisDysbiosisStaphylococcus aureusRandomized controlled trialAntimicrobialClinical trialEczema Area and Severity IndexMicrobiomeInternal medicinePharmacodynamicsDermatologyGastroenterologyAdverse effectMicrobiologyPharmacokineticsDiseaseBioinformaticsBacteriaBiologyGeneticsDermatology and Skin DiseasesAntimicrobial Peptides and ActivitiesProbiotics and Fermented Foods