Rapid electrochemical detection of MiRNA-21 facilitated by the excellent catalytic ability of Pt@CeO<sub>2</sub> nanospheres
Peiwu Chen, Lan Jiang, Xian-Jin Xie, Dong Sun, Jinyao Liu, Yuefeng Zhao, Yuhao Li, Abel Ibrahim Balbín Tamayo, Baolin Liu, Yuqing Miao, Ruizhuo Ouyang
Abstract
in a wide linear concentration range from 10 fM to 1 nM with the detection limit as low as 1.41 fM. The results achieved with this new RNA sensor were quite satisfactory during the blood sample analysis.
Topics & Concepts
ElectrochemistryCatalysismicroRNANanotechnologyChemistryChemical engineeringMaterials scienceElectrodeBiochemistryPhysical chemistryGeneEngineeringAdvanced biosensing and bioanalysis techniquesMicroRNA in disease regulationRNA Interference and Gene Delivery