Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos
Lijia Li, Fang-Nong Lai, Ling Liu, Xukun Lu, Xiaoyu Hu, Bofeng Liu, Zili Lin, Qiang Fan, Feng Kong, Qianhua Xu, Wei Xie
Topics & Concepts
BiologyCell biologySOX2Transcription factorInner cell massCell fate determinationEmbryonic stem cellTotipotentGeneticsEmbryoTrophoblastGeneEmbryogenesisBlastocystPlacentaFetusPregnancyGenomics and Chromatin DynamicsPluripotent Stem Cells ResearchCRISPR and Genetic Engineering