Targeting the mitochondrial permeability transition pore for drug discovery: Challenges and opportunities
Ibrahim Damilare Boyenle, Abdul-Quddus Kehinde Oyedele, Abdeen Tunde Ogunlana, Aishat Folashade Adeyemo, Faith Sunday Oyelere, Olateju Balikis Akinola, Temitope Isaac Adelusi, Leonard Ona Ehigie, Adeola Folasade Ehigie
Topics & Concepts
Mitochondrial permeability transition poreVoltage-dependent anion channelMPTPDrug discoveryMitochondrial membrane transport proteinMitochondrionInner mitochondrial membraneBiologyCell biologyChemistryProgrammed cell deathBiochemistryBacterial outer membraneNeuroscienceApoptosisDopamineGeneDopaminergicEscherichia coliMitochondrial Function and PathologyATP Synthase and ATPases ResearchRNA modifications and cancer