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Integrator loss leads to dsRNA formation that triggers the integrated stress response

Apoorva Baluapuri, Nicole ChenCheng Zhao, Ryan J. Marina, Kai-Lieh Huang, Anastasia Kuzkina, Maria Elisa Amodeo, Chad B. Stein, Lucie Ahn, Jordan S. Farr, Ashleigh E. Schaffer, Vikram Khurana, Eric J. Wagner, Karen Adelman

2025Cell20 citationsDOIOpen Access PDF

Topics & Concepts

BiologyIntegratorCell biologyFight-or-flight responseStress (linguistics)RNA silencingRNAGeneticsRNA interferencePhysicsGeneLinguisticsPhilosophyVoltageQuantum mechanicsRNA regulation and diseaseRNA Interference and Gene DeliveryExtracellular vesicles in disease
Integrator loss leads to dsRNA formation that triggers the integrated stress response | Litcius