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Medication-Induced Gastroparesis: A Case Report

M Ammar Kalas, Gian Galura, Richard W. McCallum

2021Journal of Investigative Medicine High Impact Case Reports39 citationsDOIOpen Access PDF

Abstract

Gastroparesis is a commonly diagnosed gastrointestinal disorder with a high prevalence globally and high disease burden to those afflicted with it. Etiologies are variable with idiopathic and diabetes being the most common causes of gastroparesis. Management of gastroparesis depends on the etiology, and accurate diagnosis is required for better targeted therapy. Medication-induced gastroparesis is reversible, and discontinuing the medication is generally curative. This case report discusses 2 cases of medication-induced gastroparesis which were initially diagnosed as diabetic gastroparesis, and thorough history taking revealed the cause to be medication induced. Repeat studies following medication discontinuation revealed improvement in symptoms and resolution of gastroparesis. Further research needs to be done to assess the frequency of misdiagnosing diabetic patients with gastroparesis due to medications, specifically glucagon-like peptide-1 receptor agonists which are increasingly being used in diabetics.

Topics & Concepts

GastroparesisMedicineDiscontinuationEtiologyDiabetes mellitusPediatricsDiseaseInternal medicineIntensive care medicineGastric emptyingStomachEndocrinologyGastrointestinal motility and disordersPharmacology and Obesity TreatmentDiet and metabolism studies
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